Esterification Delivers a Functional Enzyme into a Human Cell
A major hurdle in chemical biology is the delivery of native proteins into the cytosol of mammalian cells. Herein, we report that esterification of the carboxyl groups of an enzyme with a diazo compound enables not only its passage into the cytosol but also the retention of its catalytic activity th...
मुख्य लेखकों: | , , |
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अन्य लेखक: | |
स्वरूप: | लेख |
भाषा: | English |
प्रकाशित: |
American Chemical Society (ACS)
2020
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ऑनलाइन पहुंच: | https://hdl.handle.net/1721.1/123443 |