Collagen Prolyl 4-Hydroxylase as a Therapeutic Target
Collagen is the dominant protein of the extracellular matrix. Its distinguishing feature is a three-stranded helix of great tensile strength. (2S,4R)-4-Hydroxyproline residues are essential for the stability of this triple helix. These residues arise from the post-translational modification of (2S)-...
Main Authors: | Vasta, James D., Raines, Ronald T |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS)
2020
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Online Access: | https://hdl.handle.net/1721.1/123552 |
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