Affinity-based capture and identification of protein effectors of the growth regulator ppGpp
The nucleotide ppGpp is a highly conserved regulatory molecule in bacteria that helps tune growth rate to nutrient availability. Despite decades of study, how ppGpp regulates growth remains poorly understood. Here, we developed and validated a capture-compound mass spectrometry approach that identif...
Main Authors: | Wang, Boyuan, Dai, Peng, Ding, David, Del Rosario, Amanda M, Grant, Robert A, Pentelute, Bradley L., Laub, Michael T |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | English |
Published: |
Springer Science and Business Media LLC
2020
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Online Access: | https://hdl.handle.net/1721.1/123670 |
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