Geometric control of bacterial surface accumulation

Controlling and suppressing bacterial accumulation at solid surfaces is essential for preventing biofilm formation and biofouling. Whereas various chemical surface treatments are known to reduce cell accumulation and attachment, the role of complex surface geometries remains less well understood. He...

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Bibliographic Details
Main Authors: Mok, Rachel V. (Rachel Verla), Dunkel, Jörn, Kantsler, Vasily
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: American Physical Society (APS) 2020
Online Access:https://hdl.handle.net/1721.1/124163
Description
Summary:Controlling and suppressing bacterial accumulation at solid surfaces is essential for preventing biofilm formation and biofouling. Whereas various chemical surface treatments are known to reduce cell accumulation and attachment, the role of complex surface geometries remains less well understood. Here, we report experiments and simulations that explore the effects of locally varying boundary curvature on the scattering and accumulation dynamics of swimming Escherichia coli bacteria in quasi-two-dimensional microfluidic channels. Our experimental and numerical results show that a concave periodic boundary geometry can decrease the average cell concentration at the boundary by more than 50% relative to a flat surface.© 2019 American Physical Society.