Complex inter-relationship of body mass index, gender and serum creatinine on survival: exploring the obesity paradox in melanoma patients treated with checkpoint inhibition

A male gender driven obesity paradox (improved survival for overweight/obese patients compared to normal weight) was recently shown in melanoma in the context of checkpoint inhibition (anti-PD-1/anti-CTLA4 monotherapy) in a pooled meta-analysis. We characterized the relationship of Body Mass Index (...

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Bibliographic Details
Main Authors: Naik, Girish, Waikar, Sushrut S., Johnson, Alistair Edward William, Buchbinder, Elizabeth I., Haq, Rizwan, Hodi, F. Stephen, Schoenfeld, Jonathan D., Ott, Patrick A.
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: BioMed Central 2020
Online Access:https://hdl.handle.net/1721.1/124317