Universal amplification-free molecular diagnostics by billion-fold hierarchical nanofluidic concentration
Rapid and reliable detection of ultralow-abundance nucleic acids and proteins in complex biological media may greatly advance clinical diagnostics and biotechnology development. Currently, nucleic acid tests rely on enzymatic processes for target amplification (e.g., PCR), which have many inherent i...
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| Format: | Article |
| Language: | English |
| Published: |
Proceedings of the National Academy of Sciences
2020
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| Online Access: | https://hdl.handle.net/1721.1/124450 |