AliTV—interactive visualization of whole genome comparisons

Whole genome alignments and comparative analysis are key methods in the quest of unraveling the dynamics of genome evolution. Interactive visualization and exploration of the generated alignments, annotations, and phylogenetic data are important steps in the interpretation of the initial results. Li...

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Main Authors: Ankenbrand, Markus J., Hohlfeld, Sonja, Förster, Frank, Hackl, Thomas
Other Authors: Massachusetts Institute of Technology. Department of Civil and Environmental Engineering
Format: Article
Published: PeerJ 2020
Online Access:https://hdl.handle.net/1721.1/124464
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author Ankenbrand, Markus J.
Hohlfeld, Sonja
Förster, Frank
Hackl, Thomas
author2 Massachusetts Institute of Technology. Department of Civil and Environmental Engineering
author_facet Massachusetts Institute of Technology. Department of Civil and Environmental Engineering
Ankenbrand, Markus J.
Hohlfeld, Sonja
Förster, Frank
Hackl, Thomas
author_sort Ankenbrand, Markus J.
collection MIT
description Whole genome alignments and comparative analysis are key methods in the quest of unraveling the dynamics of genome evolution. Interactive visualization and exploration of the generated alignments, annotations, and phylogenetic data are important steps in the interpretation of the initial results. Limitations of existing software inspired us to develop our new tool AliTV, which provides interactive visualization of whole genome alignments. AliTV reads multiple whole genome alignments or automatically generates alignments from the provided data. Optional feature annotations and phylo- genetic information are supported. The user-friendly, web-browser based and highly customizable interface allows rapid exploration and manipulation of the visualized data as well as the export of publication-ready high-quality figures. AliTV is freely available at https://github.com/AliTVTeam/AliTV.
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spelling mit-1721.1/1244642022-09-29T22:38:44Z AliTV—interactive visualization of whole genome comparisons Ankenbrand, Markus J. Hohlfeld, Sonja Förster, Frank Hackl, Thomas Massachusetts Institute of Technology. Department of Civil and Environmental Engineering Whole genome alignments and comparative analysis are key methods in the quest of unraveling the dynamics of genome evolution. Interactive visualization and exploration of the generated alignments, annotations, and phylogenetic data are important steps in the interpretation of the initial results. Limitations of existing software inspired us to develop our new tool AliTV, which provides interactive visualization of whole genome alignments. AliTV reads multiple whole genome alignments or automatically generates alignments from the provided data. Optional feature annotations and phylo- genetic information are supported. The user-friendly, web-browser based and highly customizable interface allows rapid exploration and manipulation of the visualized data as well as the export of publication-ready high-quality figures. AliTV is freely available at https://github.com/AliTVTeam/AliTV. 2020-03-31T19:25:52Z 2020-03-31T19:25:52Z 2017-06 2017-04 Article http://purl.org/eprint/type/JournalArticle 2376-5992 https://hdl.handle.net/1721.1/124464 Ankenbrand MJ et al. AliTV—interactive visualization of whole genome comparisons. PeerJ Computer Science 3 (June 2017): e116 © 2017 The Authors http://dx.doi.org/10.7717/peerj-cs.116 PeerJ Computer Science Creative Commons Attribution 4.0 International license https://creativecommons.org/licenses/by/4.0/ application/pdf PeerJ PeerJ Computer Science
spellingShingle Ankenbrand, Markus J.
Hohlfeld, Sonja
Förster, Frank
Hackl, Thomas
AliTV—interactive visualization of whole genome comparisons
title AliTV—interactive visualization of whole genome comparisons
title_full AliTV—interactive visualization of whole genome comparisons
title_fullStr AliTV—interactive visualization of whole genome comparisons
title_full_unstemmed AliTV—interactive visualization of whole genome comparisons
title_short AliTV—interactive visualization of whole genome comparisons
title_sort alitv interactive visualization of whole genome comparisons
url https://hdl.handle.net/1721.1/124464
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