Sequestration of microRNA-mediated target repression by the Ago2-associated RNA-binding protein FAM120A

Sequestration of microRNA-mediated target repression by the Ago2-associated RNA-binding protein FAM120A

Argonaute (Ago) proteins interact with various binding partners and play a pivotal role in microRNA (miRNA)-mediated silencing pathways. By utilizing immunoprecipitation followed by mass spectrometry to determine cytoplasmic Ago2 protein complexes in mouse embryonic stem cells (mESCs), we identified...

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Bibliographic Details
Main Authors: Kelly, Timothy J., Suzuki, Hiroshi I., Zamudio, Jesse R., Suzuki, Megumu
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory Press 2020
Subjects:
Molecular Biology
Online Access:https://hdl.handle.net/1721.1/124507

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