MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer

MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer

Tumors display increased uptake and processing of nutrients to fulfill the demands of rapidly proliferating cancer cells. Seminal studies have shown that the proto-oncogene MYC promotes metabolic reprogramming by altering glutamine uptake and metabolism in cancer cells. How MYC regulates the metabol...

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Bibliographic Details
Main Authors: Braverman, Jonathan, Yilmaz, Omer H.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Cold Spring Harbor Laboratory 2020
Subjects:
Developmental Biology
Genetics
Online Access:https://hdl.handle.net/1721.1/124607

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