Gene-guided discovery and engineering of branched cyclic peptides in plants

The plant kingdom contains vastly untapped natural product chemistry, which has been traditionally explored through the activity-guided approach. Here, we describe a gene-guided approach to discover and engineer a class of plant ribosomal peptides, the branched cyclic lyciumins. Initially isolated f...

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Bibliographic Details
Main Authors: Kersten, Roland D., Weng, Jing-Ke
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences 2020
Subjects:
Online Access:https://hdl.handle.net/1721.1/124661