Clostridioides difficile-Associated Antibiotics Alter Human Mucosal Barrier Functions by Microbiome-Independent Mechanisms

Clostridioides difficile-Associated Antibiotics Alter Human Mucosal Barrier Functions by Microbiome-Independent Mechanisms

A clinically relevant risk factor forClostridioides difficile-associated dis-ease (CDAD) is recent antibiotic treatment. Although broad-spectrum antibioticshave been shown to disrupt the structure of the gut microbiota, some antibioticsappear to increase CDAD risk without being highly active against...

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Bibliographic Details
Main Authors: Kester, Jemila C., Brubaker, Douglas K., Velazquez, Jason, Wright, Charles, Lauffenburger, Douglas A., Griffith, Linda G.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: American Society for Microbiology 2020
Subjects:
Pharmacology (medical)
Pharmacology
Infectious Diseases
Online Access:https://hdl.handle.net/1721.1/124762

Internet

https://hdl.handle.net/1721.1/124762

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