Altered Binding of Tumor Antigenic Peptides to MHC Class I Affects CD8+ T Cell–Effector Responses
T-cell priming occurs when a na€ve T cell recognizes cognate peptide–MHC complexes on an activated antigen-presenting cell. The circumstances of this initial priming have ramifications on the fate of the newly primed T cell. Newly primed CD8þ T cells can embark onto different trajectories, with some...
Main Authors: | , |
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Other Authors: | |
Format: | Article |
Language: | English |
Published: |
American Association for Cancer Research (AACR)
2020
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Online Access: | https://hdl.handle.net/1721.1/124836 |