Altered Binding of Tumor Antigenic Peptides to MHC Class I Affects CD8+ T Cell–Effector Responses

Altered Binding of Tumor Antigenic Peptides to MHC Class I Affects CD8+ T Cell–Effector Responses

T-cell priming occurs when a na€ve T cell recognizes cognate peptide–MHC complexes on an activated antigen-presenting cell. The circumstances of this initial priming have ramifications on the fate of the newly primed T cell. Newly primed CD8þ T cells can embark onto different trajectories, with some...

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Bibliographic Details
Main Authors:	Devlin, Christine A., Birnbaum, Michael E.
Other Authors:	Koch Institute for Integrative Cancer Research at MIT
Format:	Article
Language:	English
Published:	American Association for Cancer Research (AACR) 2020
Online Access:	https://hdl.handle.net/1721.1/124836

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