Incomplete base excision repair contributes to cell death from antibiotics and other stresses
Numerous lethal stresses in bacteria including antibiotics, thymineless death, and MalE-LacZ expression trigger an increase in the production of reactive oxygen species. This results in the oxidation of the nucleotide pool by radicals produced by Fenton chemistry. Following the incorporation of thes...
Main Authors: | Gruber, Charley C., Walker, Graham C. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | English |
Published: |
Elsevier BV
2020
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Online Access: | https://hdl.handle.net/1721.1/124921 |
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