Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate

In this issue of Molecular Cell, Cheng et al. report specific and dose-dependent gene expression changes resulting from decreased ribosome levels, including distinct gene expression signatures resulting from loss of genes encoding members of either the large or small ribosomal subunit.

Bibliographic Details
Main Authors: Mertins, Philipp, Regev, Aviv
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Elsevier BV 2020
Subjects:
Online Access:https://hdl.handle.net/1721.1/125016
Description
Summary:In this issue of Molecular Cell, Cheng et al. report specific and dose-dependent gene expression changes resulting from decreased ribosome levels, including distinct gene expression signatures resulting from loss of genes encoding members of either the large or small ribosomal subunit.