Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate
In this issue of Molecular Cell, Cheng et al. report specific and dose-dependent gene expression changes resulting from decreased ribosome levels, including distinct gene expression signatures resulting from loss of genes encoding members of either the large or small ribosomal subunit.
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| Format: | Article |
| Language: | English |
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Elsevier BV
2020
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| Online Access: | https://hdl.handle.net/1721.1/125016 |
| _version_ | 1811070647791517696 |
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| author | Mertins, Philipp Regev, Aviv |
| author2 | Massachusetts Institute of Technology. Department of Biology |
| author_facet | Massachusetts Institute of Technology. Department of Biology Mertins, Philipp Regev, Aviv |
| author_sort | Mertins, Philipp |
| collection | MIT |
| description | In this issue of Molecular Cell, Cheng et al. report specific and dose-dependent gene expression changes resulting from decreased ribosome levels, including distinct gene expression signatures resulting from loss of genes encoding members of either the large or small ribosomal subunit. |
| first_indexed | 2024-09-23T08:39:22Z |
| format | Article |
| id | mit-1721.1/125016 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T08:39:22Z |
| publishDate | 2020 |
| publisher | Elsevier BV |
| record_format | dspace |
| spelling | mit-1721.1/1250162022-09-30T10:18:57Z Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate Mertins, Philipp Regev, Aviv Massachusetts Institute of Technology. Department of Biology Koch Institute for Integrative Cancer Research at MIT Cell Biology Molecular Biology In this issue of Molecular Cell, Cheng et al. report specific and dose-dependent gene expression changes resulting from decreased ribosome levels, including distinct gene expression signatures resulting from loss of genes encoding members of either the large or small ribosomal subunit. National Institutes of Health (U.S.) (Grant DP2-GM-119138) National Institutes of Health (U.S.) (Grant P50-GM-31535) Alfred P. Sloan Foundation (Investigator Award FG-2016–6229) Pew Charitable Trusts (Grant 00029624) National Human Genome Research Institute (U.S.). Centers of Excellence in Genomic Science (Grant P50 HG006193) 2020-05-05T16:57:59Z 2020-05-05T16:57:59Z 2019-01 2020-01-28T18:41:53Z Article http://purl.org/eprint/type/JournalArticle 1097-2765 https://hdl.handle.net/1721.1/125016 Cheng, Ze et al. “Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate.” Molecular Cell 73 (2019): 36-47 © 2019 The Author(s) en 10.1016/j.molcel.2018.10.032 Molecular Cell Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier BV PMC |
| spellingShingle | Cell Biology Molecular Biology Mertins, Philipp Regev, Aviv Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate |
| title | Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate |
| title_full | Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate |
| title_fullStr | Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate |
| title_full_unstemmed | Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate |
| title_short | Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate |
| title_sort | small and large ribosomal subunit deficiencies lead to distinct gene expression signatures that reflect cellular growth rate |
| topic | Cell Biology Molecular Biology |
| url | https://hdl.handle.net/1721.1/125016 |
| work_keys_str_mv | AT mertinsphilipp smallandlargeribosomalsubunitdeficienciesleadtodistinctgeneexpressionsignaturesthatreflectcellulargrowthrate AT regevaviv smallandlargeribosomalsubunitdeficienciesleadtodistinctgeneexpressionsignaturesthatreflectcellulargrowthrate |