Inflammatory regulatory network mediated by the joint action of NF-kB, STAT3, and AP-1 factors is involved in many human cancers

Using an inducible, inflammatory model of breast cellular transformation, we describe the transcriptional regulatory network mediated by STAT3, NF-κB, and AP-1 factors on a genomic scale. These proinflammatory regulators form transcriptional complexes that directly regulate the expression of hundred...

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Bibliographic Details
Main Author: Regev, Aviv
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences 2020
Online Access:https://hdl.handle.net/1721.1/125026

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