Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

Gliomas with histone H3 lysine27-to-methionine mutations (H3K27M-glioma) arise primarily in the midline of the central nervous system of young children, suggesting a cooperation between genetics and cellular context in tumorigenesis. Although the genetics of H3K27M-glioma are well characterized, the...

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Bibliographic Details
Main Author:	Regev, Aviv
Other Authors:	Massachusetts Institute of Technology. Department of Biology
Format:	Article
Language:	English
Published:	American Association for the Advancement of Science (AAAS) 2020
Online Access:	https://hdl.handle.net/1721.1/125052

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