CRISPR-mediated modeling and functional validation of candidate tumor suppressor genes in small cell lung cancer
Small cell lung cancer (SCLC) is a highly aggressive subtype of lung cancer that remains among the most lethal of solid tumor malignancies. Recent genomic sequencing studies have identified many recurrently mutated genes in human SCLC tumors. However, the functional roles of most of these genes rema...
| Main Authors: | , , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Proceedings of the National Academy of Sciences
2020
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| Subjects: | |
| Online Access: | https://hdl.handle.net/1721.1/125148 |
