Systems and Synthetic microRNA Biology: From Biogenesis to Disease Pathogenesis
MicroRNAs (miRNAs) are approximately 22-nucleotide-long, small non-coding RNAs that post-transcriptionally regulate gene expression. The biogenesis of miRNAs involves multiple steps, including the transcription of primary miRNAs (pri-miRNAs), nuclear Drosha-mediated processing, cytoplasmic Dicer-med...
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2020
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| Online Access: | https://hdl.handle.net/1721.1/125355 |