The Stringent Response Inhibits DNA Replication Initiation in E. coli by Modulating Supercoiling of oriC
The stringent response enables bacteria to respond to a variety of environmental stresses, especially various forms of nutrient limitation. During the stringent response, the cell produces large quantities of the nucleotide alarmone ppGpp, which modulates many aspects of cell physiology, including r...
| Main Authors: | , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
American Society for Microbiology
2020
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| Online Access: | https://hdl.handle.net/1721.1/125385 |