Ionizable Amino-Polyesters Synthesized via Ring Opening Polymerization of Tertiary Amino-Alcohols for Tissue Selective mRNA Delivery
The utility of messenger RNA (mRNA) as a therapy is gaining a broad interest due to its potential for addressing a wide range of diseases, while effective delivery of mRNA molecules to various tissues still poses a challenge. This study reports on the design and characterization of new ionizable ami...
Main Authors: | Kowalski, Piotr S, Palmiero, Umberto Capasso, Huang, Yuxuan, Rudra, Arnab, Langer, Robert S, Anderson, Daniel Griffith |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemical Engineering |
Format: | Article |
Language: | English |
Published: |
Wiley
2020
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Online Access: | https://hdl.handle.net/1721.1/125442 |
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