An Adaptable Platform for Directed Evolution in Human Cells
The discovery and optimization of biomolecules that reliably function in metazoan cells is imperative for both the study of basic biology and the treatment of disease. We describe the development, characterization, and proof-of-concept application of a platform for directed evolution of diverse biom...
Main Authors: | Berman, Chet Michael., Papa, Louis John, Hendel, Samuel J., Moore, Christopher Lawrence, Suen, Patreece H., Weickhardt, Alexander F., Doan, Ngoc Duc, Kumar, Caiden M., Butty, Vincent L. G., Shoulders, Matthew D. |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS)
2020
|
Online Access: | https://hdl.handle.net/1721.1/125551 |
Similar Items
-
Directed evolution in mammalian cells
by: Hendel, Samuel J, et al.
Published: (2022) -
A cysteine-based molecular code informs collagen C-propeptide assembly
by: DiChiara, Andrew Stephen, et al.
Published: (2020) -
Directed evolution in human cells via adenoviral replication
by: Berman, Chet Michael.
Published: (2019) -
A Processive Protein Chimera Introduces Mutations across Defined DNA Regions In Vivo
by: Moore, Christopher Lawrence, et al.
Published: (2020) -
A cysteine-based molecular code informs collagen C-propeptide assembly
by: Andrew S. DiChiara, et al.
Published: (2018-10-01)