Initial Biochemical and Functional Evaluation of Murine Calprotectin Reveals Ca(II)-Dependence and Its Ability to Chelate Multiple Nutrient Transition Metal Ions

Initial Biochemical and Functional Evaluation of Murine Calprotectin Reveals Ca(II)-Dependence and Its Ability to Chelate Multiple Nutrient Transition Metal Ions

Calprotectin (CP) is an abundant host-defense protein that contributes to the metal-withholding innate immune response by sequestering nutrient metal ions from microbial pathogens in the extracellular space. Over the past decade, murine models of infectious disease have advanced understanding of the...

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Detalles Bibliográficos
Autores principales: Hadley, Rose Currier, Gu, Yu, Nolan, Elizabeth Marie
Otros Autores: Massachusetts Institute of Technology. Department of Chemistry
Formato: Artículo
Lenguaje:English
Publicado: American Chemical Society (ACS) 2020
Acceso en línea:https://hdl.handle.net/1721.1/125595

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