Native Zinc Catalyzes Selective and Traceless Release of Small Molecules in β-Cells

Copyright © 2020 American Chemical Society. The loss of insulin-producing β-cells is the central pathological event in type 1 and 2 diabetes, which has led to efforts to identify molecules to promote β-cell proliferation, protection, and imaging. However, the lack of β-cell specificity of these mole...

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Bibliographic Details
Main Authors: Goldberg, Jacob Michael, Lippard, Stephen J.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: American Chemical Society (ACS) 2020
Online Access:https://hdl.handle.net/1721.1/125660