“Inactive” ingredients in oral medications
Oral forms of medications contain "inactive" ingredients to enhance their physical properties. Using data analytics, we characterized the abundance and complexity of inactive ingredients in approved medications. A majority of medications contain ingredients that could cause adverse reactio...
| Main Authors: | , , , , , , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
American Association for the Advancement of Science (AAAS)
2020
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| Online Access: | https://hdl.handle.net/1721.1/125869 |
| _version_ | 1826206141559865344 |
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| author | Reker, Daniel Blum, Steven M. Steiger, Christoph Winfried Johannes Anger, Kevin E. Sommer, Jamie M. Fanikos, John Traverso, Carlo Giovanni |
| author2 | Massachusetts Institute of Technology. Department of Mechanical Engineering |
| author_facet | Massachusetts Institute of Technology. Department of Mechanical Engineering Reker, Daniel Blum, Steven M. Steiger, Christoph Winfried Johannes Anger, Kevin E. Sommer, Jamie M. Fanikos, John Traverso, Carlo Giovanni |
| author_sort | Reker, Daniel |
| collection | MIT |
| description | Oral forms of medications contain "inactive" ingredients to enhance their physical properties. Using data analytics, we characterized the abundance and complexity of inactive ingredients in approved medications. A majority of medications contain ingredients that could cause adverse reactions, underscoring the need to maximize the tolerability and safety of medications and their inactive ingredients. |
| first_indexed | 2024-09-23T13:24:45Z |
| format | Article |
| id | mit-1721.1/125869 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T13:24:45Z |
| publishDate | 2020 |
| publisher | American Association for the Advancement of Science (AAAS) |
| record_format | dspace |
| spelling | mit-1721.1/1258692022-09-28T14:00:50Z “Inactive” ingredients in oral medications Reker, Daniel Blum, Steven M. Steiger, Christoph Winfried Johannes Anger, Kevin E. Sommer, Jamie M. Fanikos, John Traverso, Carlo Giovanni Massachusetts Institute of Technology. Department of Mechanical Engineering Koch Institute for Integrative Cancer Research at MIT Oral forms of medications contain "inactive" ingredients to enhance their physical properties. Using data analytics, we characterized the abundance and complexity of inactive ingredients in approved medications. A majority of medications contain ingredients that could cause adverse reactions, underscoring the need to maximize the tolerability and safety of medications and their inactive ingredients. National Instutites of Health (Grant EB000244) 2020-06-18T19:29:01Z 2020-06-18T19:29:01Z 2019-03 2018-07 2020-06-18T17:50:58Z Article http://purl.org/eprint/type/JournalArticle 1946-6234 1946-6242 https://hdl.handle.net/1721.1/125869 Reker, Daniel et al. '"Inactive" ingredients in oral medications.' Science Translational Medicine 11, 483 (March 2019): eaau6753 © 2019 The Authors en http://dx.doi.org/10.1126/scitranslmed.aau6753 Science Translational Medicine Creative Commons Attribution-Noncommercial-Share Alike http://creativecommons.org/licenses/by-nc-sa/4.0/ application/pdf application/pdf American Association for the Advancement of Science (AAAS) Daniel Reker |
| spellingShingle | Reker, Daniel Blum, Steven M. Steiger, Christoph Winfried Johannes Anger, Kevin E. Sommer, Jamie M. Fanikos, John Traverso, Carlo Giovanni “Inactive” ingredients in oral medications |
| title | “Inactive” ingredients in oral medications |
| title_full | “Inactive” ingredients in oral medications |
| title_fullStr | “Inactive” ingredients in oral medications |
| title_full_unstemmed | “Inactive” ingredients in oral medications |
| title_short | “Inactive” ingredients in oral medications |
| title_sort | inactive ingredients in oral medications |
| url | https://hdl.handle.net/1721.1/125869 |
| work_keys_str_mv | AT rekerdaniel inactiveingredientsinoralmedications AT blumstevenm inactiveingredientsinoralmedications AT steigerchristophwinfriedjohannes inactiveingredientsinoralmedications AT angerkevine inactiveingredientsinoralmedications AT sommerjamiem inactiveingredientsinoralmedications AT fanikosjohn inactiveingredientsinoralmedications AT traversocarlogiovanni inactiveingredientsinoralmedications |