The epitranscriptomic writer ALKBH8 drives tolerance and protects mouse lungs from the environmental pollutant naphthalene

The epitranscriptomic writer ALKBH8 drives tolerance and protects mouse lungs from the environmental pollutant naphthalene

The epitranscriptomic writer Alkylation Repair Homolog 8 (ALKBH8) is a transfer RNA (tRNA) methyltransferase that modifies the wobble uridine of selenocysteine tRNA to promote the specialized translation of selenoproteins. Using Alkbh8 deficient (Alkbh8def) mice, we have investigated the importance...

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Bibliographic Details
Main Authors: Leonardi, Andrea, Kovalchuk, Nataliia, Yin, Lei, Endres, Lauren, Evke, Sara, Nevins, Steven, Martin, Samuel, Dedon, Peter C., Melendez, J. Andres, Van Winkle, Laura, Zhang, Qing-Yu, Ding, Xinxin, Begley, Thomas J
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Informa UK Limited 2020
Online Access:https://hdl.handle.net/1721.1/125909

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