Translating preclinical models to humans

Generalizing results from animal models to human patients is a critical biomedical challenge. This problem is a key cause of the large proportion of failures encountered in moving therapeutics from preclinical studies to clinical trials (1). Direct translation of observations in rodents or nonhuman...

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Bibliographic Details
Main Authors: Brubaker, Douglas, Lauffenburger, Douglas A.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: American Association for the Advancement of Science (AAAS) 2020
Online Access:https://hdl.handle.net/1721.1/125911

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