Translating preclinical models to humans
Generalizing results from animal models to human patients is a critical biomedical challenge. This problem is a key cause of the large proportion of failures encountered in moving therapeutics from preclinical studies to clinical trials (1). Direct translation of observations in rodents or nonhuman...
Main Authors: | Brubaker, Douglas, Lauffenburger, Douglas A. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Language: | English |
Published: |
American Association for the Advancement of Science (AAAS)
2020
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Online Access: | https://hdl.handle.net/1721.1/125911 |
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