Fast Magic-Angle-Spinning 19F Spin Exchange NMR for Determining Nanometer 19F-19F Distances in Proteins and Pharmaceutical Compounds
Internuclear distances measured using NMR provide crucial constraints of three-dimensional structures but are often restricted to about 5 Å due to the weakness of nuclear-spin dipolar couplings. For studying macromolecular assemblies in biology and materials science, distance constraints beyond 1 nm...
Main Authors: | Roos, Matthias, Wang, Tuo, Shcherbakov, Alexander Aleksandrovich, Hong, Mei |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Language: | English |
Published: |
American Chemical Society (ACS)
2020
|
Online Access: | https://hdl.handle.net/1721.1/125915 |
Similar Items
-
Determination of long-range distances by fast magic-angle-spinning radiofrequency-driven 19 F-19 F dipolar recoupling NMR
by: Roos, Matthias, et al.
Published: (2020) -
Rapid measurement of long-range distances in proteins by multidimensional 13C–19F REDOR NMR under fast magic-angle spinning
by: Shcherbakov, Alexander Aleksandrovich, et al.
Published: (2020) -
Two-dimensional 19F–13C correlation NMR for 19F resonance assignment of fluorinated proteins
by: Shcherbakov, Alexander A, et al.
Published: (2021) -
Rapid Proton-Detected NMR Assignment for Proteins with Fast Magic Angle Spinning
by: Barbet-Massin, Emeline, et al.
Published: (2017) -
Accurate Determination of Interstrand Distances and Alignment in Amyloid Fibrils by Magic Angle Spinning NMR
by: Bajaj, Vikram S., et al.
Published: (2012)