Assessment of Biological Role and Insight into Druggability of the Plasmodium falciparum Protease Plasmepsin V

Upon infecting a red blood cell (RBC), the malaria parasite Plasmodium falciparum drastically remodels its host by exporting hundreds of proteins into the RBC cytosol. This protein export program is essential for parasite survival. Hence export-related proteins could be potential drug targets. One e...

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Bibliographic Details
Main Authors: Polino, Alexander J., Nasamu, Armiyaw S., Niles, Jacquin, Goldberg, Daniel E.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: American Chemical Society (ACS) 2020
Online Access:https://hdl.handle.net/1721.1/125998