Facile Solid-Phase Synthesis and Assessment of Nucleoside Analogs as Inhibitors of Bacterial UDP-Sugar Processing Enzymes
The privileged uptake of nucleosides into cells has generated interest in the development of nucleoside-analog libraries for mining new inhibitors. Of particular interest are applications in the discovery of substrate mimetic inhibitors for the growing number of identified glycan-processing enzymes...
Principais autores: | Madec, Amaël G. E., Schocker, Nathaniel S, Sanchini, Silvano, Myratgeldiyev, Gadam, Das, Debasis, Imperiali, Barbara |
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Outros Autores: | Massachusetts Institute of Technology. Department of Biology |
Formato: | Artigo |
Idioma: | English |
Publicado em: |
American Chemical Society (ACS)
2020
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Acesso em linha: | https://hdl.handle.net/1721.1/126011 |
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