Facile Solid-Phase Synthesis and Assessment of Nucleoside Analogs as Inhibitors of Bacterial UDP-Sugar Processing Enzymes

The privileged uptake of nucleosides into cells has generated interest in the development of nucleoside-analog libraries for mining new inhibitors. Of particular interest are applications in the discovery of substrate mimetic inhibitors for the growing number of identified glycan-processing enzymes...

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Detalhes bibliográficos
Principais autores: Madec, Amaël G. E., Schocker, Nathaniel S, Sanchini, Silvano, Myratgeldiyev, Gadam, Das, Debasis, Imperiali, Barbara
Outros Autores: Massachusetts Institute of Technology. Department of Biology
Formato: Artigo
Idioma:English
Publicado em: American Chemical Society (ACS) 2020
Acesso em linha:https://hdl.handle.net/1721.1/126011

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