PEt3-mediated deoxygenative C N coupling of nitroarenes and boronic acids
A method for the preparation of aryl- and heteroarylamine products by triethylphosphine-mediated deoxygenative coupling of nitroarenes and boronic acids is reported. This method provides access to an array of functionalized (hetero)arylamine products from readily available starting materials under t...
| Príomhchruthaitheoirí: | , , |
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| Formáid: | Alt |
| Teanga: | English |
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Elsevier BV
2020
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| Rochtain ar líne: | https://hdl.handle.net/1721.1/126126 |
| _version_ | 1826201035473944576 |
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| author | Nykaza, Trevor Vincent Yang, Junyu Radosevich, Alexander T. |
| author2 | Massachusetts Institute of Technology. Department of Chemistry |
| author_facet | Massachusetts Institute of Technology. Department of Chemistry Nykaza, Trevor Vincent Yang, Junyu Radosevich, Alexander T. |
| author_sort | Nykaza, Trevor Vincent |
| collection | MIT |
| description | A method for the preparation of aryl- and heteroarylamine products by triethylphosphine-mediated deoxygenative coupling of nitroarenes and boronic acids is reported. This method provides access to an array of functionalized (hetero)arylamine products from readily available starting materials under the action of an inexpensive commercial reagent. The developed triethylphosphine-mediated transformation highlights the capability of organophosphorus compounds to carry out this useful deoxygenative transformation without the necessity of any transition metal additives. |
| first_indexed | 2024-09-23T11:45:20Z |
| format | Article |
| id | mit-1721.1/126126 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T11:45:20Z |
| publishDate | 2020 |
| publisher | Elsevier BV |
| record_format | dspace |
| spelling | mit-1721.1/1261262022-09-27T21:43:01Z PEt3-mediated deoxygenative C N coupling of nitroarenes and boronic acids Nykaza, Trevor Vincent Yang, Junyu Radosevich, Alexander T. Massachusetts Institute of Technology. Department of Chemistry A method for the preparation of aryl- and heteroarylamine products by triethylphosphine-mediated deoxygenative coupling of nitroarenes and boronic acids is reported. This method provides access to an array of functionalized (hetero)arylamine products from readily available starting materials under the action of an inexpensive commercial reagent. The developed triethylphosphine-mediated transformation highlights the capability of organophosphorus compounds to carry out this useful deoxygenative transformation without the necessity of any transition metal additives. National Institute of General Medical Sciences (NIGMS) (Grant GM114547) 2020-07-10T15:39:34Z 2020-07-10T15:39:34Z 2019-06 2019-02 2020-06-19T18:01:59Z Article http://purl.org/eprint/type/JournalArticle 0040-4020 https://hdl.handle.net/1721.1/126126 Nykaza, Trevor V. et al. "PEt3-mediated deoxygenative CN coupling of nitroarenes and boronic acids." Tetrahedron 75, 24 (June 2019): 3248-3252 © 2019 Elsevier en http://dx.doi.org/10.1016/j.tet.2019.03.035 Tetrahedron Creative Commons Attribution-NonCommercial-NoDerivs License http://creativecommons.org/licenses/by-nc-nd/4.0/ application/pdf Elsevier BV PMC |
| spellingShingle | Nykaza, Trevor Vincent Yang, Junyu Radosevich, Alexander T. PEt3-mediated deoxygenative C N coupling of nitroarenes and boronic acids |
| title | PEt3-mediated deoxygenative C N coupling of nitroarenes and boronic acids |
| title_full | PEt3-mediated deoxygenative C N coupling of nitroarenes and boronic acids |
| title_fullStr | PEt3-mediated deoxygenative C N coupling of nitroarenes and boronic acids |
| title_full_unstemmed | PEt3-mediated deoxygenative C N coupling of nitroarenes and boronic acids |
| title_short | PEt3-mediated deoxygenative C N coupling of nitroarenes and boronic acids |
| title_sort | pet3 mediated deoxygenative c n coupling of nitroarenes and boronic acids |
| url | https://hdl.handle.net/1721.1/126126 |
| work_keys_str_mv | AT nykazatrevorvincent pet3mediateddeoxygenativecncouplingofnitroarenesandboronicacids AT yangjunyu pet3mediateddeoxygenativecncouplingofnitroarenesandboronicacids AT radosevichalexandert pet3mediateddeoxygenativecncouplingofnitroarenesandboronicacids |