A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus

A Role for Fc Function in Therapeutic Monoclonal Antibody-Mediated Protection against Ebola Virus

The recent Ebola virus (EBOV) epidemic highlighted the need for effective vaccines and therapeutics to limit and prevent outbreaks. Host antibodies against EBOV are critical for controlling disease, and recombinant monoclonal antibodies (mAbs) can protect from infection. However, antibodies mediate...

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Bibliographic Details
Main Authors: Yu, Wen-Han, Das, Jishnu, Lauffenburger, Douglas A, Alter, Galit
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Language:English
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/126177

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