Formulations for trans-tympanic antibiotic delivery
We have developed a drug delivery system for prolonged trans-tympanic antibiotic delivery from a single dose administration. Increased permeability to ciprofloxacin of the intact tympanic membrane (TM) was achieved by chemical permeation enhancers (CPEs - bupivacaine, limonene, sodium dodecyl sulfat...
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Bibliographic Details
| Main Authors: |
Khoo, Xiaojuan,
Simons, Emmanuel John,
Chiang, Homer H.,
Hickey, Julia M.,
Sabharwal, Vishakha,
Pelton, Stephen I.,
Rosowski, John J,
Langer, Robert,
Kohane, Daniel S |
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| Other Authors: |
Harvard University--MIT Division of Health Sciences and Technology |
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| Format: | Article
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| Language: | English |
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| Published: |
Elsevier BV
2020
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| Online Access: | https://hdl.handle.net/1721.1/126215
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