Formulations for trans-tympanic antibiotic delivery

Formulations for trans-tympanic antibiotic delivery

We have developed a drug delivery system for prolonged trans-tympanic antibiotic delivery from a single dose administration. Increased permeability to ciprofloxacin of the intact tympanic membrane (TM) was achieved by chemical permeation enhancers (CPEs - bupivacaine, limonene, sodium dodecyl sulfat...

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Bibliographic Details
Main Authors: Khoo, Xiaojuan, Simons, Emmanuel John, Chiang, Homer H., Hickey, Julia M., Sabharwal, Vishakha, Pelton, Stephen I., Rosowski, John J, Langer, Robert, Kohane, Daniel S
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:English
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/126215

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