Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications
© 2019 IOP Publishing Ltd. The first ever demonstration of temporal focusing with short wave infrared (SWIR) excitation and emission is demonstrated, achieving a penetration depth of 500 μm in brain tissue. This is substantially deeper than the highest previously-reported values for temporal focusin...
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Format: | Article |
Language: | English |
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IOP Publishing
2020
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Online Access: | https://hdl.handle.net/1721.1/126241 |
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author | Rowlands, Christopher J. Bruns, Oliver T. Franke, Daniel Fukamura, Dai Jain, Rakesh K. Bawendi, Moungi G. So, Peter T.C. |
author2 | Massachusetts Institute of Technology. Department of Chemistry |
author_facet | Massachusetts Institute of Technology. Department of Chemistry Rowlands, Christopher J. Bruns, Oliver T. Franke, Daniel Fukamura, Dai Jain, Rakesh K. Bawendi, Moungi G. So, Peter T.C. |
author_sort | Rowlands, Christopher J. |
collection | MIT |
description | © 2019 IOP Publishing Ltd. The first ever demonstration of temporal focusing with short wave infrared (SWIR) excitation and emission is demonstrated, achieving a penetration depth of 500 μm in brain tissue. This is substantially deeper than the highest previously-reported values for temporal focusing imaging in brain tissue, and demonstrates the value of these optimized wavelengths for neurobiological applications. |
first_indexed | 2024-09-23T13:24:26Z |
format | Article |
id | mit-1721.1/126241 |
institution | Massachusetts Institute of Technology |
language | English |
last_indexed | 2024-09-23T13:24:26Z |
publishDate | 2020 |
publisher | IOP Publishing |
record_format | dspace |
spelling | mit-1721.1/1262412022-09-28T13:57:39Z Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications Rowlands, Christopher J. Bruns, Oliver T. Franke, Daniel Fukamura, Dai Jain, Rakesh K. Bawendi, Moungi G. So, Peter T.C. Massachusetts Institute of Technology. Department of Chemistry © 2019 IOP Publishing Ltd. The first ever demonstration of temporal focusing with short wave infrared (SWIR) excitation and emission is demonstrated, achieving a penetration depth of 500 μm in brain tissue. This is substantially deeper than the highest previously-reported values for temporal focusing imaging in brain tissue, and demonstrates the value of these optimized wavelengths for neurobiological applications. NIH (grant no. 9-P41-EB015871-26A1) NIH (grant no. 5-U54-CA151884) ARO (grant no. W911NF-13-D-0001) NSF (grant no. ECCS-1449291) 2020-07-17T18:55:26Z 2020-07-17T18:55:26Z 2019-04 2019-12-12T17:48:48Z Article http://purl.org/eprint/type/JournalArticle 1361-6463 https://hdl.handle.net/1721.1/126241 Rowlands, Christopher J. et al. "Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications." Journal of Physics D: Applied Physics 52, 26 (Apr. 2019): doi 10.1088/1361-6463/AB16B4 ©2019 Author(s) en 10.1088/1361-6463/AB16B4 Journal of Physics D: Applied Physics Creative Commons Attribution 3.0 unported license https://creativecommons.org/licenses/by/3.0/ application/pdf IOP Publishing IOP Publishing |
spellingShingle | Rowlands, Christopher J. Bruns, Oliver T. Franke, Daniel Fukamura, Dai Jain, Rakesh K. Bawendi, Moungi G. So, Peter T.C. Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications |
title | Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications |
title_full | Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications |
title_fullStr | Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications |
title_full_unstemmed | Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications |
title_short | Increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications |
title_sort | increasing the penetration depth of temporal focusing multiphoton microscopy for neurobiological applications |
url | https://hdl.handle.net/1721.1/126241 |
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