OnTAD: hierarchical domain structure reveals the divergence of activity among TADs and boundaries

The spatial organization of chromatin in the nucleus has been implicated in regulating gene expression. Maps of high-frequency interactions between different segments of chromatin have revealed topologically associating domains (TADs), within which most of the regulatory interactions are thought to...

Full description

Bibliographic Details
Main Authors: An, Lin, Yang, Tao, Yang, Jiahao, Nubler, Johannes, Xiang, Guanjue, Hardison, Ross C, Li, Qunhua, Zhang, Yu
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Language:English
Published: BioMed Central 2020
Online Access:https://hdl.handle.net/1721.1/126320