OnTAD: hierarchical domain structure reveals the divergence of activity among TADs and boundaries
The spatial organization of chromatin in the nucleus has been implicated in regulating gene expression. Maps of high-frequency interactions between different segments of chromatin have revealed topologically associating domains (TADs), within which most of the regulatory interactions are thought to...
Main Authors: | An, Lin, Yang, Tao, Yang, Jiahao, Nubler, Johannes, Xiang, Guanjue, Hardison, Ross C, Li, Qunhua, Zhang, Yu |
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Other Authors: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
Format: | Article |
Language: | English |
Published: |
BioMed Central
2020
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Online Access: | https://hdl.handle.net/1721.1/126320 |
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