Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells

Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells

Carcinoma cells residing in an intermediate phenotypic state along the epithelial–mesenchymal (E–M) spectrum are associated with malignant phenotypes, such as invasiveness, tumor-initiating ability, and metastatic dissemination. Using the recently described CD104+/CD44hi antigen marker combination,...

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Bibliographic Details
Main Authors: Kröger, Cornelia, Afeyan, Alexander, Mraz, Jasmin, Eaton, Elinor Ng, Reinhardt, Ferenc, Thiru, Prathapan, Bierie, Brian, Ye, Xin, Weinberg, Robert A
Other Authors: Whitehead Institute for Biomedical Research
Format: Article
Language:English
Published: Proceedings of the National Academy of Sciences 2020
Online Access:https://hdl.handle.net/1721.1/126342

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