Blood Pressure and the Risk of Acute Kidney Injury in the ICU: Case-Control Versus Case-Crossover Designs

This chapter describes two different approaches—a case-control and a case-crossover design—to examine the effect of transient exposure of hypotension on the risk of acute kidney injury (AKI) in intensive care unit (ICU) patients. We highlight the key differences and the design rationale of these two...

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Main Authors: Lehman, Li-wei H., Feng, Mengling, Yang, Yijun, Mark, Roger G
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Book
Language:English
Published: Springer International Publishing 2020
Online Access:https://hdl.handle.net/1721.1/126405
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author Lehman, Li-wei H.
Feng, Mengling
Yang, Yijun
Mark, Roger G
author2 Massachusetts Institute of Technology. Department of Biological Engineering
author_facet Massachusetts Institute of Technology. Department of Biological Engineering
Lehman, Li-wei H.
Feng, Mengling
Yang, Yijun
Mark, Roger G
author_sort Lehman, Li-wei H.
collection MIT
description This chapter describes two different approaches—a case-control and a case-crossover design—to examine the effect of transient exposure of hypotension on the risk of acute kidney injury (AKI) in intensive care unit (ICU) patients. We highlight the key differences and the design rationale of these two approaches, and present preliminary findings from applying these techniques to study the relationship between hypotension and AKI using the MIMIC II database.
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spelling mit-1721.1/1264052022-10-01T09:38:22Z Blood Pressure and the Risk of Acute Kidney Injury in the ICU: Case-Control Versus Case-Crossover Designs Lehman, Li-wei H. Feng, Mengling Yang, Yijun Mark, Roger G Massachusetts Institute of Technology. Department of Biological Engineering This chapter describes two different approaches—a case-control and a case-crossover design—to examine the effect of transient exposure of hypotension on the risk of acute kidney injury (AKI) in intensive care unit (ICU) patients. We highlight the key differences and the design rationale of these two approaches, and present preliminary findings from applying these techniques to study the relationship between hypotension and AKI using the MIMIC II database. 2020-07-27T20:35:27Z 2020-07-27T20:35:27Z 2016 2019-10-09T15:26:55Z Book http://purl.org/eprint/type/BookItem 9783319437408 9783319437422 https://hdl.handle.net/1721.1/126405 Lehman, Li-wei H.et al. "Blood Pressure and the Risk of Acute Kidney Injury in the ICU: Case-Control Versus Case-Crossover Designs." Secondary Analysis of Electronic Health Records, edited by MIT Critical Data, Springer International Publishing, 2016, 369-375. © 2016 The Author(s) en http://dx.doi.org/10.1007/978-3-319-43742-2_25 Secondary Analysis of Electronic Health Records Creative Commons Attribution NonCommercial License 4.0 https://creativecommons.org/licenses/by-nc/4.0/ application/pdf Springer International Publishing Springer
spellingShingle Lehman, Li-wei H.
Feng, Mengling
Yang, Yijun
Mark, Roger G
Blood Pressure and the Risk of Acute Kidney Injury in the ICU: Case-Control Versus Case-Crossover Designs
title Blood Pressure and the Risk of Acute Kidney Injury in the ICU: Case-Control Versus Case-Crossover Designs
title_full Blood Pressure and the Risk of Acute Kidney Injury in the ICU: Case-Control Versus Case-Crossover Designs
title_fullStr Blood Pressure and the Risk of Acute Kidney Injury in the ICU: Case-Control Versus Case-Crossover Designs
title_full_unstemmed Blood Pressure and the Risk of Acute Kidney Injury in the ICU: Case-Control Versus Case-Crossover Designs
title_short Blood Pressure and the Risk of Acute Kidney Injury in the ICU: Case-Control Versus Case-Crossover Designs
title_sort blood pressure and the risk of acute kidney injury in the icu case control versus case crossover designs
url https://hdl.handle.net/1721.1/126405
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