REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease

REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease

Show other versions (1)

The molecular basis of the earliest neuronal changes that lead to Alzheimer’s disease (AD) is unclear. Here, we analyze neural cells derived from sporadic AD (SAD), APOE4 gene-edited and control induced pluripotent stem cells (iPSCs). We observe major differences in iPSC-derived neural progenitor (N...

Full description

Bibliographic Details
Main Authors: Meyer, Katharina, Feldman, Heather M., Lu, Tao, Drake, Derek, Lim, Elaine T., Ling, King-Hwa, Bishop, Nicholas A., Pan, Ying, Seo, Jinsoo, Lin, Yuan-Ta, Su, Susan C. (Susan Chih-Chieh), Church, George M., Tsai, Li-Huei, Yankner, Bruce A.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Language:English
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/126408

Internet

https://hdl.handle.net/1721.1/126408

Similar Items