Illuminating the human virome in health and disease
Although the microbiome is established as an important regulator of health and disease, the role of viruses that inhabit asymptomatic humans (collectively, the virome) is less defined. While we are still characterizing what constitutes a healthy or diseased virome, an exciting next step is to move b...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
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Springer Science and Business Media LLC
2020
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| Online Access: | https://hdl.handle.net/1721.1/126475 |
| _version_ | 1826207313453645824 |
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| author | Adiliaghdam, Fatemeh Jeffrey, Kate |
| author2 | Massachusetts Institute of Technology. Center for Microbiome Informatics and Therapeutics |
| author_facet | Massachusetts Institute of Technology. Center for Microbiome Informatics and Therapeutics Adiliaghdam, Fatemeh Jeffrey, Kate |
| author_sort | Adiliaghdam, Fatemeh |
| collection | MIT |
| description | Although the microbiome is established as an important regulator of health and disease, the role of viruses that inhabit asymptomatic humans (collectively, the virome) is less defined. While we are still characterizing what constitutes a healthy or diseased virome, an exciting next step is to move beyond correlations and toward identification of specific viruses and their precise mechanisms of beneficial or harmful immunomodulation. Illuminating this will represent a first step toward developing virome-focused therapies. |
| first_indexed | 2024-09-23T13:47:43Z |
| format | Article |
| id | mit-1721.1/126475 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T13:47:43Z |
| publishDate | 2020 |
| publisher | Springer Science and Business Media LLC |
| record_format | dspace |
| spelling | mit-1721.1/1264752022-09-28T16:15:27Z Illuminating the human virome in health and disease Adiliaghdam, Fatemeh Jeffrey, Kate Massachusetts Institute of Technology. Center for Microbiome Informatics and Therapeutics Although the microbiome is established as an important regulator of health and disease, the role of viruses that inhabit asymptomatic humans (collectively, the virome) is less defined. While we are still characterizing what constitutes a healthy or diseased virome, an exciting next step is to move beyond correlations and toward identification of specific viruses and their precise mechanisms of beneficial or harmful immunomodulation. Illuminating this will represent a first step toward developing virome-focused therapies. National Institutes of Health (Grants R21AI144877, R01DK119996) National Center for Advancing Translational Sciences (Award UL-1TR002541) 2020-08-05T17:51:15Z 2020-08-05T17:51:15Z 2020-07 2020-07 2020-08-02T03:48:40Z Article http://purl.org/eprint/type/JournalArticle 1756-994X https://hdl.handle.net/1721.1/126475 Adiliaghdam, Fatemeh and Kate L. Jeffrey. "Illuminating the human virome in health and disease." Genome Medicine 12, 1 (July 2020): 66 © 2020 Springer Nature en http://dx.doi.org/10.1186/s13073-020-00766-x Genome Medicine Creative Commons Attribution https://creativecommons.org/licenses/by/4.0/ The Author(s) application/pdf Springer Science and Business Media LLC BioMed Central |
| spellingShingle | Adiliaghdam, Fatemeh Jeffrey, Kate Illuminating the human virome in health and disease |
| title | Illuminating the human virome in health and disease |
| title_full | Illuminating the human virome in health and disease |
| title_fullStr | Illuminating the human virome in health and disease |
| title_full_unstemmed | Illuminating the human virome in health and disease |
| title_short | Illuminating the human virome in health and disease |
| title_sort | illuminating the human virome in health and disease |
| url | https://hdl.handle.net/1721.1/126475 |
| work_keys_str_mv | AT adiliaghdamfatemeh illuminatingthehumanviromeinhealthanddisease AT jeffreykate illuminatingthehumanviromeinhealthanddisease |