Systematic analysis of the intersection of disease mutations with protein modifications
BACKGROUND: Perturbed posttranslational modification (PTM) landscapes commonly cause pathological phenotypes. The Cancer Genome Atlas (TCGA) project profiles thousands of tumors allowing the identification of spontaneous cancer-driving mutations, while Uniprot and dbSNP manage genetic disease-associ...
Main Authors: | Simpson, Claire M., Zhang, Bin, Hornbeck, Peter V, Gnad, Florian |
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Other Authors: | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
Format: | Article |
Language: | English |
Published: |
BioMed Central
2020
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Online Access: | https://hdl.handle.net/1721.1/126552 |
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