Modeling of Collective Cell Behaviors Interacting With Extracellular Matrix Using Dual Faceted Linearization

Cells interacting over an extracellular matrix (ECM) exhibit emergent behaviors, which are often observably different from single-cell dynamics. Fibroblasts embedded in a 3-D ECM, for example, compact the surrounding gel and generate an anisotropic strain field, which cannot be observed in single ce...

Full description

Bibliographic Details
Main Authors: Mayalu, Michaëlle N., Kim, Min-Cheol, Asada, Haruhiko
Other Authors: Massachusetts Institute of Technology. Department of Mechanical Engineering
Format: Article
Language:English
Published: American Society of Mechanical Engineers 2020
Online Access:https://hdl.handle.net/1721.1/126812