Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis

Intra- and Inter-cellular Rewiring of the Human Colon during Ulcerative Colitis

Genome-wide association studies (GWAS) have revealed risk alleles for ulcerative colitis (UC). To understand their cell type specificities and pathways of action, we generate an atlas of 366,650 cells from the colon mucosa of 18 UC patients and 12 healthy individuals, revealing 51 epithelial, stroma...

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Bibliographic Details
Main Authors: Ordovas-Montanes, Jose Manuel, Graham, Daniel B., Shalek, Alexander K, Xavier, Ramnik Joseph, Regev, Aviv
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/126822

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