The Pneumococcal Iron Uptake Protein A (PiuA) Specifically Recognizes Tetradentate FeIIIbis- and Mono-Catechol Complexes

The Pneumococcal Iron Uptake Protein A (PiuA) Specifically Recognizes Tetradentate FeIIIbis- and Mono-Catechol Complexes

Streptococcus pneumoniae (Spn) is an important Gram-positive human pathogen that causes millions of infections worldwide with an increasing occurrence of antibiotic resistance. Fe acquisition is a crucial virulence determinant in Spn; further, Spn relies on exogenous FeIII-siderophore scavenging to...

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Bibliographic Details
Main Authors: Zhang, Yifan, Edmonds, Katherine A., Raines, Daniel J., Murphy, Brennan A., Wu, Hongwei, Guo, Chuchu, Nolan, Elizabeth Marie, VanNieuwenhze, Michael S., Duhme-Klair, Anne-K., Giedroc, David P.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: Elsevier BV 2020
Online Access:https://hdl.handle.net/1721.1/128018

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