Single-Molecule Fluorescence Detection of the Epidermal Growth Factor Receptor in Membrane Discs

Single-Molecule Fluorescence Detection of the Epidermal Growth Factor Receptor in Membrane Discs

The epidermal growth factor receptor (EGFR) is critical to normal cellular signaling pathways. Moreover, it has been implicated in a range of pathologies, including cancer. As a result, it is the primary target of many anticancer drugs. One limitation to the design and development of these drugs has...

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Bibliographic Details
Main Authors: Quinn, Steven D., Srinivasan, Shwetha, Gordon, Jesse B., He, Wei, Carraway, Kermit L., Coleman, Matthew A., Schlau-Cohen, Gabriela S
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Language:English
Published: American Chemical Society (ACS) 2020
Online Access:https://hdl.handle.net/1721.1/128242

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