Microfluidic platform for three-dimensional cell culture under spatiotemporal heterogeneity of oxygen tension
Cells in a tumor microenvironment are exposed to spatial and temporal variations in oxygen tension due to hyperproliferation and immature vascularization. Such spatiotemporal oxygen heterogeneity affects the behavior of cancer cells, leading to cancer growth and metastasis, and thus, it is essential...
Main Authors: | Koens, Rei, Tabata, Yugo, Serrano, Jean Carlos, Aratake, Satoshi, Yoshino, Daisuke, Kamm, Roger Dale, Funamoto, Kenichi |
---|---|
Other Authors: | Massachusetts Institute of Technology. Department of Mechanical Engineering |
Format: | Article |
Language: | English |
Published: |
AIP Publishing
2020
|
Online Access: | https://hdl.handle.net/1721.1/128366 |
Similar Items
-
Tension, Free Space, and Cell Damage in a Microfluidic Wound Healing Assay
by: Murrell, Michael, et al.
Published: (2012) -
Microfluidic platform for the reproduction of hypoxic vascular microenvironments
by: Naoyuki Takahashi, et al.
Published: (2023-04-01) -
A novel microfluidic platform for high-resolution imaging of a three-dimensional cell culture under a controlled hypoxic environment
by: Funamoto, Kenichi, et al.
Published: (2014) -
Differentiation of Embryonic Stem Cells into Cardiomyocytes in a Microfluidic System
by: Wan, Chen-Rei, et al.
Published: (2012) -
Oxygen levels in thermoplastic microfluidic devices during cell culture
by: Ochs, Christopher J., et al.
Published: (2015)