Cerebellar Functional Anatomy: a Didactic Summary Based on Human fMRI Evidence
The cerebellum is relevant for virtually all aspects of behavior in health and disease. Cerebellar findings are common across all kinds of neuroimaging studies of brain function and dysfunction. A large and expanding body of literature mapping motor and non-motor functions in the healthy human cereb...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Article |
| Language: | English |
| Published: |
Springer US
2020
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| Online Access: | https://hdl.handle.net/1721.1/128511 |
| _version_ | 1811073176778571776 |
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| author | Guell Paradis, Xavier Schmahmann, Jeremy |
| author2 | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences |
| author_facet | Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences Guell Paradis, Xavier Schmahmann, Jeremy |
| author_sort | Guell Paradis, Xavier |
| collection | MIT |
| description | The cerebellum is relevant for virtually all aspects of behavior in health and disease. Cerebellar findings are common across all kinds of neuroimaging studies of brain function and dysfunction. A large and expanding body of literature mapping motor and non-motor functions in the healthy human cerebellar cortex using fMRI has served as a tool for interpreting these findings. For example, results of cerebellar atrophy in Alzheimer’s disease in caudal aspects of Crus I/II and medial lobule IX can be interpreted by consulting a large number of task, resting-state, and gradient-based reports that describe the functional characteristics of these specific aspects of the cerebellar cortex. Here, we provide a concise summary that outlines organizational principles observed consistently across these studies of normal cerebellar organization. This basic framework may be useful for investigators performing or reading experiments that require a functional interpretation of human cerebellar topography. |
| first_indexed | 2024-09-23T09:29:34Z |
| format | Article |
| id | mit-1721.1/128511 |
| institution | Massachusetts Institute of Technology |
| language | English |
| last_indexed | 2024-09-23T09:29:34Z |
| publishDate | 2020 |
| publisher | Springer US |
| record_format | dspace |
| spelling | mit-1721.1/1285112022-09-30T14:45:50Z Cerebellar Functional Anatomy: a Didactic Summary Based on Human fMRI Evidence Guell Paradis, Xavier Schmahmann, Jeremy Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences The cerebellum is relevant for virtually all aspects of behavior in health and disease. Cerebellar findings are common across all kinds of neuroimaging studies of brain function and dysfunction. A large and expanding body of literature mapping motor and non-motor functions in the healthy human cerebellar cortex using fMRI has served as a tool for interpreting these findings. For example, results of cerebellar atrophy in Alzheimer’s disease in caudal aspects of Crus I/II and medial lobule IX can be interpreted by consulting a large number of task, resting-state, and gradient-based reports that describe the functional characteristics of these specific aspects of the cerebellar cortex. Here, we provide a concise summary that outlines organizational principles observed consistently across these studies of normal cerebellar organization. This basic framework may be useful for investigators performing or reading experiments that require a functional interpretation of human cerebellar topography. 2020-11-17T22:02:41Z 2020-11-17T22:02:41Z 2019-11 2020-09-24T21:45:56Z Article http://purl.org/eprint/type/JournalArticle 1473-4230 1473-4222 https://hdl.handle.net/1721.1/128511 Guell, Xavier and Jeremy Schmahmann. "Cerebellar Functional Anatomy: a Didactic Summary Based on Human fMRI Evidence." Cerebellum 19 (November 2019): 1-5 © 2019 Springer Science Business Media, LLC en https://doi.org/10.1007/s12311-019-01083-9 Cerebellum Article is made available in accordance with the publisher's policy and may be subject to US copyright law. Please refer to the publisher's site for terms of use. Springer Science+Business Media, LLC, part of Springer Nature application/pdf Springer US Springer US |
| spellingShingle | Guell Paradis, Xavier Schmahmann, Jeremy Cerebellar Functional Anatomy: a Didactic Summary Based on Human fMRI Evidence |
| title | Cerebellar Functional Anatomy: a Didactic Summary Based on Human fMRI Evidence |
| title_full | Cerebellar Functional Anatomy: a Didactic Summary Based on Human fMRI Evidence |
| title_fullStr | Cerebellar Functional Anatomy: a Didactic Summary Based on Human fMRI Evidence |
| title_full_unstemmed | Cerebellar Functional Anatomy: a Didactic Summary Based on Human fMRI Evidence |
| title_short | Cerebellar Functional Anatomy: a Didactic Summary Based on Human fMRI Evidence |
| title_sort | cerebellar functional anatomy a didactic summary based on human fmri evidence |
| url | https://hdl.handle.net/1721.1/128511 |
| work_keys_str_mv | AT guellparadisxavier cerebellarfunctionalanatomyadidacticsummarybasedonhumanfmrievidence AT schmahmannjeremy cerebellarfunctionalanatomyadidacticsummarybasedonhumanfmrievidence |