A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite

A human monoclonal antibody prevents malaria infection by targeting a new site of vulnerability on the parasite

Development of a highly effective vaccine or antibodies for the prevention and ultimately elimination of malaria is urgently needed. Here we report the isolation of a number of human monoclonal antibodies directed against the Plasmodium falciparum (Pf) circumsporozoite protein (PfCSP) from several s...

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Bibliographic Details
Main Authors: Kisalu, Neville K, Idris, Azza H, Weidle, Connor, Flores-Garcia, Yevel, Flynn, Barbara J, Sack, Brandon K, Murphy, Sean, Schön, Arne, Freire, Ernesto, Francica, Joseph R, Miller, Alex B, Gregory, Jason, March-Riera, Sandra, Liao, Hua-Xin, Haynes, Barton F, Wiehe, Kevin, Trama, Ashley M, Saunders, Kevin O, Gladden, Morgan A, Monroe, Anthony, Bonsignori, Mattia, Kanekiyo, Masaru, Wheatley, Adam K, McDermott, Adrian B, Farney, S Katie, Chuang, Gwo-Yu, Zhang, Baoshan, Kc, Natasha, Chakravarty, Sumana, Kwong, Peter D, Sinnis, Photini, Bhatia, Sangeeta N, Kappe, Stefan H I, Sim, B Kim Lee, Hoffman, Stephen L, Zavala, Fidel, Pancera, Marie, Seder, Robert A
Other Authors: Harvard University--MIT Division of Health Sciences and Technology
Format: Article
Language:English
Published: Springer Science and Business Media LLC 2020
Online Access:https://hdl.handle.net/1721.1/128661

Internet

https://hdl.handle.net/1721.1/128661

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